What makes this formula so effective?
Mg Optima Relax focuses on promoting the effects of Gamma-aminobutyric acid (GABA). GABA is a naturally occurring chemical in the brain (neurotransmitter). The main role of GABA is to have a calming effect on your nervous system. Magnesium - functions as a GABA receptor agonist promoting the effects of GABA.
Medlabs use the best quality Magnesium in the form of bisglycinate chelate. This means its highly absorbable and gentle on the bowels. Some brands use cheaper forms of magnesium which have a poor absorption rates.
Theanine - an amino acid found in Green Tea. It promotes relaxation via binding to glutamate receptors and inducing alpha wave (the normal electrical activity of the brain when conscious and relaxed) brain activity.
L-Glutamine - a precursor to GABA production, therefore enhancing the effect of the magnesium.
Pyridoxal 5 Phosphate (Vitamin B6) - is a vital cofactor for the enzyme Glutamate Decarboxylase that is essential in the synthesis of GABA.
Zinc – Along with many other health benefits Zinc is a modulator of both excitatory and inhibitory neurotransmission, therefore it plays an important role in maintaining and improving relaxation during times of stress.
Drugs such as Valium & Xanax work to enhance the effect of GABA, Alcohol is believed to mimic GABA's effect in the brain. Mg Optima Relax naturally assists the effects of GABA to calm the body.
WARNING: If symptoms persist consult your healthcare practitioner. Vitamin supplements should not replace a balanced diet. Contains less than 15 mg caffeine per 5 g dose. REFERENCES: 1. Held K, Antonijevic IA, et al. Oral Mg(2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry 2002;35:135-43. 2. Eulenburg V, Armsen W, et al. Glycine transporters: essential regulators of neurotransmission. Trends Biochem Sci 2005;30:325-33. 3. Walls AB, Waagepetersen HS, et al. The glutamine-glutamate/GABA cycle: function, regional differences in glutamate and GABA production and effects of interference with GABA metabolism. Neurochem Res 2015;40:402-9. 4. Kimura K, Ozeki M, et al. L-Theanine reduces psychological and physiological stress responses. Biol Psychol 2007;74:39-45. 5. Jasmin L, Wu MV, et al. GABA puts a stop to pain. Curr Drug Targets CNS Neurol Disord 2004;3:487-505. 6. Takeda A, Minami A, et al. Differential effects of zinc on glutamatergic and GABAergic neurotransmitter systems in the hippocampus. J Neurosci Res 2004;75:225-9. 7. Ross SM. L-theanine (suntheanin): effects of L-theanine, an amino acid derived from Camellia sinensis (green tea), on stress response parameters. Holist Nurs Pract 2014;28:65-8. 8. Schwellnus MP, Derman EW, et al. Aetiology of skeletal muscle 'cramps' during exercise: a novel hypothesis. J Sports Sci 1997;15:277-85. 9. Yoto A, Motoki M, et al. Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses J Physiol Anthropol 2012;31:28 10. Talebi M, Goldust M. Oral magnesium; migraine prophylaxis. J Pak Med Assoc. 2013;63:286. 11. Peikert A, Wilimzig C, et al. Prophylaxis of migraine with oral magnesium: results from a prospective, multi-center, placebo-controlled and double-blind randomized study. Cephalalgia;16:257-63. 12. Owens DF, Krieg Stein AR. Is there more to GABA than synaptic inhibition? Nature Rev Neuroscience 2002;3:715. 13. Gecz, J. Glutamate receptors and learning and memory. Nature Genetics 2010;42:925